The A.C. Camargo Cancer Center (ACC) is a nonprofit institution and one of the largest cancer centers in Latin America. ACC mission includes integration of scientific research and cancer treatment. According to the Scimago Institutions Rank 2011-2014 the ACC is the health institution that has the highest quality publications in Brazil. ACC presents exceptional capacity of patient’s recruitment, community outreach and highly specialized medical care. Its scientific research unit gathers a Biobank with approximately 62,000 samples (excluding paraffin-blocks) associated with comprehensive clinical information. The research center provides state-of-art genomics and bioinformatics, cell biology, molecular pathology, animal facilities and molecular imaging. The connection between clinicians and basic scientists creates a solid scenario for innovative patient care.